Why not stress unnecessarily with how you need to travel all over the country at night or early in the morning? Take advantage of being a weekend and set off on your journey the day before. Thanks to this you will not have to go anywhere in the night, but you will arrive in the evening and sleep peacefully. Take advantage of cheap accommodation in Prague.
The day before
You know it, you really care about going anywhere by car or train on time and what won't happen. There's a huge column on the highway, or the train was stuck in the station. At such a moment there will be nothing more to you than to sweat, why you have not come before and accept that you are late or that you are not at all. Cheap accommodation Prague could save you at such a moment if you decide to go a day earlier.